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Image Search Results
Journal: Antibiotics
Article Title: Baicalein Inhibits Streptococcus mutans Biofilms and Dental Caries-Related Virulence Phenotypes
doi: 10.3390/antibiotics10020215
Figure Lengend Snippet: ( A ) CLSM (Confocal Laser Scanning Microscopy) micrographs illustrating the effect on the sub-inhibitory concentration of baicalein (200 µM) on biofilm architecture and viability of the biofilm cells through Live/Dead staining. Baicalein treated cell cultures show sparing green color cells with no confluent mass, indicating inhibition of biofilm formation. ( B ) COMSTAT analysis of the CLSM images revealed a reduction in the biofilm biomass, average thickness, and diffusion distances in the baicalein treated biofilms compared to the untreated control. ( C ) ImageJ analysis shows the proportion of viable cells in the biofilm formed with baicalein treatment at the concentration of 200 µM (MBIC 50 ).
Article Snippet: Z-stacks were obtained from at least 5 regions and the obtained images were further analyzed using
Techniques: Confocal Laser Scanning Microscopy, Concentration Assay, Staining, Inhibition, Diffusion-based Assay, Control